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PANCREATIC ISLETS
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DeCS
Descriptor
English
:
Islets of Langerhans
Descriptor
Spanish
:
Islotes Pancreáticos
Descriptor
Portuguese
:
Ilhotas Pancreáticas
Synonyms
English
:
Islands of Langerhans
Islet Cells
Nesidioblasts
Pancreas, Endocrine
Pancreatic Islets
Tree Number:
A03.734.414
A06.407.414
Definition
English
:
Irregular microscopic structures consisting of cords of
endocrine cells
that are scattered throughout the
PANCREAS
among the exocrine acini. Each islet is surrounded by
connective tissue
fibers and penetrated by a network of
capillaries
. There are four major cell types. The most abundant beta cells (50-80%) secrete
INSULIN
. Alpha cells (5-20%) secrete
GLUCAGON
. PP cells (10-35%) secrete
PANCREATIC POLYPEPTIDE
. Delta cells (~5%) secrete
SOMATOSTATIN.
Indexing Annotation
English
:
do not confuse with
LANGERHANS CELLS
(skin);
neoplasms
=
ADENOMA
, ISLET CELL or
CARCINOMA
, ISLET CELL or their specifics
Entry Combination - descr/qualif
English
:
Islets of Langerhans
/
transplantation
use
Islets of Langerhans Transplantation
History Note
English
:
91; was ISLANDS OF LANGERHANS 1963-90
Allowable Qualifiers
English
:
AB
abnormalities
AH
anatomy & histology
BS
blood supply
CH
chemistry
CY
cytology
DE
drug effects
EM
embryology
EN
enzymology
GD
growth & development
IM
immunology
IN
injuries
IR
innervation
ME
metabolism
MI
microbiology
PS
parasitology
PA
pathology
PH
physiology
PP
physiopathology
RE
radiation effects
RA
radiography
RI
radionuclide imaging
SE
secretion
SU
surgery
US
ultrasonography
UL
ultrastructure
VI
virology
Record Number:
29211
Unique Identifier:
D007515
Occurrence in VHL
:
Similar:
DeCS
CID-10
SciELO
LILACS
LIS